You can use Disk Utility System Restore or Carbon Copy Cloner to clone your internal hard drive or any bootable volume to the ARC-8050. It will be able to boot your modern Intel based Mac whether connected via USB 3.0 (ARC-5026 only), or Thunderbolt.
Tags: ARC-5026, ARC-8050, boot, Q80031311, Thunderbolt, USB 3.0